Vexation
Part of speech: noun
Definition: The act of annoying, vexing, or irritating. The state of being vexed or irritated.
Annoyance
Part of speech: noun
Definition: That which annoys.An act or instance of annoying.The psychological state of being annoyed or irritated.
Example sentence: When I'm painting and in the zone, it's difficult for me to stop. It can take me half a day to get into that space, and once I do, I only talk to a certain few people who won't disrupt it. Home to sleep and back at it, nothing else outside of getting food. Everything else is an annoyance getting in my way.