Screwy
Part of speech: adjective
Definition: Crazy; silly; ridiculous; insane; demented; unreasonable. Tipsy; slightly drunk.
Insane
Part of speech: adjective
Definition: Exhibiting unsoundness or disorder of mind; not sane; mad; deranged in mind; delirious; distracted.Used by, or appropriated to, insane persons; as, an insane hospital.Causing insanity or madness.Characterized by insanity or the utmost folly; chimerical; unpractical; as, an insane plan, attempt, etc.
Example sentence: It is sometimes an appropriate response to reality to go insane.