Incurable
Part of speech: adjective
Definition: Of an illness, condition, etc, that cannot be cured.
Part of speech: noun
Definition: One who cannot be cured.
Example sentence: If your doctor tells you you have a rare disease that he or she has never seen, if you've got an incurable cancer, boy, don't accept that. You know, go and get a second opinion.
Inalterable
Part of speech: adjective
Definition: That cannot be altered.